Malaria#

Mice were bit 10 times by mosquitoes, and the number of salivary gland sporozoites detected in the mosquitoes was measured. The mice were then observed to determine whether they got malaria. Some of the mice were given a malarial antibody pre-mosquito bite.

From the authors: “Over a century since Ronald Ross discovered that malaria is caused by the bite of an infectious mosquito it is still unclear how the number of parasites injected influences disease transmission. Currently it is assumed that all mosquitoes with salivary gland sporozoites are equally infectious irrespective of the number of parasites they harbour, though this has never been rigorously tested.”

Initialization#

library(fosdata)
data <- fosdata::malaria

Accessing fields#

data <- fosdata::malaria
antibody <- data$antibody # Just a random field in the dataset

Interactive R Sample#

You can use the R editor below to interactively explore the dataset and generate plots. This contains a fully self-contained R environment with fosdata, ggplot2, and dplyr loaded.

webR + fosdata Test

Console
Plot

    


    
    

      

        No plot generated yet.
      

      scatterplot
    

  



LLM instructions#


If using an LLM, you can copy-paste the following instructions to accompany your prompt to inform the model of the fields and their types in the dataset.


LLM Instructions


The fosdata::malaria dataset containing the following fields:

fields[3]{name,type,values}:
  sporozoite,integer,n/a
  malaria,integer,n/a
  antibody,factor,[no,yes]


Fields#



  
      

          Name
          Description
          Type
          Min
          Max
          Values
      

  
  
      

          sporozoite
          The total number of sporozoites detected from the 10 bites.
          integer
          -
          32
          -
      

      

          malaria
          1 = yes malaria detected, 0 = no malaria detected
          integer
          -
          1
          -
      

      

          antibody
          yes/no did the mouse receive an antibody treatment pre-mosquito bites
          factor
          -
          -
          no, yes
      

  



Source#


Churcher TS, Sinden RE, Edwards NJ, Poulton ID, Rampling TW, Brock PM, et al. (2017) Probability of Transmission of Malaria from Mosquito to Human Is Regulated by Mosquito Parasite Density in Naïve and Vaccinated Hosts. PLoS Pathog 13(1): e1006108. https://doi.org/10.1371/journal.ppat.1006108



 
      

      

        
  





















  
  
  
  

    
    
      
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